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Loss of cell identity drives human aging: Two new papers

369 points · 184 comments · bookofjoe

  1. dyauspitr · · focus · HN ↗
    So chronic stress is one of the main contributors to aging. I hope I make it to my 40s.

    Do we currently have the ability to do targeted methylation or de methylation at sites in cells?

    1. SlightlyLeftPad · · focus · HN ↗
      Good news! Research shows that hope reduces stress! [0]

      [0]: <a href="https:&#x2F;&#x2F;www.forbes.com&#x2F;sites&#x2F;tracybrower&#x2F;2024&#x2F;09&#x2F;15&#x2F;how-being-hopeful-reduces-stress&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.forbes.com&#x2F;sites&#x2F;tracybrower&#x2F;2024&#x2F;09&#x2F;15&#x2F;how-bein...

      1. dyauspitr · · focus · HN ↗
        What about Xanax or medication. Hypothetically ignoring the ill effects of the drugs themselves will chemical stress relief have the same anti-aging benefits?
        1. Shitty-kitty · · focus · HN ↗
          They are not talking about stress in the &quot;mental health&quot; setting, rather the metabolic one.
          1. dyauspitr · · focus · HN ↗
            In most cases they are the same thing.
            1. Shitty-kitty · · focus · HN ↗
              Most of it is oxygen. Oxygen is highly reactive so the same thing that makes it a good as source of fuel, also makes it poisonous. It is a double-edged sword.
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