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Loss of cell identity drives human aging: Two new papers

369 points · 184 comments · bookofjoe

dyauspitr · 1790966547 · focus · HN ↗
So chronic stress is one of the main contributors to aging. I hope I make it to my 40s.
Do we currently have the ability to do targeted methylation or de methylation at sites in cells?
1. SlightlyLeftPad · 1790967259 · focus · HN ↗
  Good news! Research shows that hope reduces stress! [0]
  [0]: <a href="https://www.forbes.com/sites/tracybrower/2024/09/15/how-being-hopeful-reduces-stress/" rel="nofollow">https://www.forbes.com/sites/tracybrower/2024/09/15/how-bein...
  1. dyauspitr · 1790967974 · focus · HN ↗
    What about Xanax or medication. Hypothetically ignoring the ill effects of the drugs themselves will chemical stress relief have the same anti-aging benefits?
    nradov · 1790968450 · focus · HN ↗
    If you believe that HRV is inversely correlated with stress then Xanax has the opposite of your intended effect.
    Shitty-kitty · 1791009864 · focus · HN ↗
    They are not talking about stress in the "mental health" setting, rather the metabolic one.
    dyauspitr · 1791012333 · focus · HN ↗
    In most cases they are the same thing.
    Shitty-kitty · 1791017970 · focus · HN ↗
    Most of it is oxygen. Oxygen is highly reactive so the same thing that makes it a good as source of fuel, also makes it poisonous. It is a double-edged sword.

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