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Why is the liver so weirdly regenerative?

576 points · 293 comments · jbotz

  1. Aeolun · · focus · HN ↗
    I feel like this is obvious. Eventually dying of all the weird body failures doesn’t inhibit your ability to procreate, but if you cannot survive alcohol or other various poisons you’ll never make it to a fertile age.
    1. nomel · · focus · HN ↗
      Picking the wrong berry from a bush isn't so difficult. Ask me how I know. And, for my second encounter, don't think because you see an animal eating it, it's safe!
      1. cratermoon · · focus · HN ↗
        Did you know birds do not have receptors for capsaicin? They can eat any pepper and it doesn't affect them. So if you see a bird snacking on a pepper that's red or greenish-yellow, wrinkly, and has a pointy end, well ... watch out
      2. colechristensen · · focus · HN ↗
        And onions are mildly toxic to cats and dogs. There is a lot less shared responses as to what is toxic or edible across species.

        Basically every flavor compound in an herb or spice we eat is a poison directed at insects, microbes, or other creatures. (much less every medicinal or psychoactive compound found in nature)

        1. hobo123 · · focus · HN ↗
          Onion compounds slow down ALDH (aldehyde detox), not sure if for cats it's a different (i.e. yet another) mechanism though.
      3. Aeolun · · focus · HN ↗
        Doesn’t that validate my point? The liver needs to deal with this stuff unless you manage to throw it all up again.
        1. nomel · · focus · HN ↗
          Not all responses are a counterarguments. That one was very clearly supporting, anecdotal, evidence.
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