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Loss of cell identity drives human aging: Two new papers

369 points · 184 comments · bookofjoe

dyauspitr · 1790966547 · focus · HN ↗
So chronic stress is one of the main contributors to aging. I hope I make it to my 40s.
Do we currently have the ability to do targeted methylation or de methylation at sites in cells?
1. SlightlyLeftPad · 1790967259 · focus · HN ↗
  Good news! Research shows that hope reduces stress! [0]
  [0]: <a href="https://www.forbes.com/sites/tracybrower/2024/09/15/how-being-hopeful-reduces-stress/" rel="nofollow">https://www.forbes.com/sites/tracybrower/2024/09/15/how-bein...
  1. amelius · 1790968161 · focus · HN ↗
    Sadly, AI just made many of us lose all hope.
    missedthecue · 1790983058 · focus · HN ↗
    AI is an amazing Rorschach test in this regard. In the way that two people will look at it -- not just AI in general but in a specific implementation of it (coding, vidgen, etc). And one will feel deep dread and knots in their stomach while the other is filled to the brim with hope and optimism.
    I think the former group almost certainly outweighs the latter group at least in the Western hemisphere, but I know the Western hemisphere has been steeped in a deep malaise of anti-optimism for several decades preceding AI to begin with. That it's almost a game to identify all the ways anything new might be bad, rather than celebrating the obvious ways they are good. And this penchant invariably biases their developing opinions of all new technology, be it AI or anything else.
    someonebaggy · 1791032268 · focus · HN ↗
    This is not without reason, since living standards have been steadily declining since 1971, and every new technology has been explored by the rich to ensure that living standards decline faster.
    orangecat · 1791041047 · focus · HN ↗
    living standards have been steadily declining since 1971
    This is generally false, and in areas where it's arguably true the problem is usually terrible policies, e.g. forbidding people from building housing and then being shocked when homes are unaffordable. On the other hand technology has improved living standards substantially; in 1971 less than 20% of US households had a dishwasher and 30% had air conditioning.

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