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California farmers are struggling to sell grapes as demand for wine drops

389 points · 987 comments · randycupertino

  1. alexandre_m · · focus · HN ↗
    > while young people are drinking less alcohol due to health and financial concerns

    My observation is that gen-z spends less time socializing in real life, and drinking remains a social habit for the most part at a younger age. While they drink less, cannabis, vaping and psychedelics are on the rise.

    It's a nice claim to say they are more responsible, but it tells an incomplete story.

    1. 1-6 · · focus · HN ↗
      I may be old-fashioned but the substitute mind-altering drugs you're mentioning does not sound like a more responsible pathway.
      1. landdate · · focus · HN ↗

        [dead]

        1. mrob · · focus · HN ↗
          >alcohol's main mechanism is through depleting oxygen in the blood

          Blood oxygen is quickly and cheaply measured with a pulse oximeter, which shows this to be false. The primary mechanism of action of ethanol is increasing the sensitivity of some GABA receptors (similar to benzodiazepines and barbiturates). But ethanol has very complex pharmacology, which a huge number of other targets. See:

          <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Pharmacology_of_ethanol" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Pharmacology_of_ethanol

          1. landdate · · focus · HN ↗
            Okay whatever, but the point is ut decreases oxygen to the brain and causes permanent brain damage.
            1. fragmede · · focus · HN ↗
              Don&#x27;t drink alcohol if you don&#x27;t want to, you can just say no. It doesn&#x27;t cause permanent brain damage by decreasing oxygen to the brain though. The damage to the brain by alcohol from frequent repeated exposure to high doses which causes measurable brain damage comes from chemical effects. An occasional beer really isn&#x27;t going to destroy your brain.
              1. landdate · · focus · HN ↗
                Okay, but you missed my larger point which was the deaths and violence and rape and crime caused by alcohol. If you alchys want to drink it should be far away from good law respecting citizens and you cant call the police if you get hurt while drinking or utilize the hralth care system.
                1. fragmede · · focus · HN ↗
                  I&#x27;m not sure why you&#x27;re making it personal and calling me an &quot;alchy&quot;. Who are you really arguing with here? I&#x27;m not whoever wronged you, I&#x27;m just pointing out that it&#x27;s not oxygen deprivation that causes brain damage from alcohol.
                  1. landdate · · focus · HN ↗
                    Regardless your prior claim about one berr not causing brain damage is categorically false. While I was wronf about mechanism its true, even drinking in moderation causes brain damage.

                    <a href="https:&#x2F;&#x2F;www.health.harvard.edu&#x2F;mind-and-mood&#x2F;alcohol-even-in-moderation-could-harm-your-brain" rel="nofollow">https:&#x2F;&#x2F;www.health.harvard.edu&#x2F;mind-and-mood&#x2F;alcohol-even-in...

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