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Creatine uptake enhances antitumor immunity

185 points · 227 comments · lormayna

  1. nsbk · · focus · HN ↗
    This is such a crazy substance. I'm 43 and I feel like I have more energy than I have ever had before. I started taking it during recovery from a bad ankle fracture since it helps building muscle mass. Once the ankle was better I took up CrossFit, and kept on taking creatine because why not, it helps replenish ATP so I will be able to give the extra-push when working out, I thought.

    What is blowing my mind though is that at $dayjob my team is going through a crazy crunch to deliver a very strategic project and some of us are pushing 10-12h days often. I'm in hour 12 today for the second day in a row, and my head is not tired at all. Turns out the brain also uses a lot of ATP too, specially during demanding cognitive tasks so I guess it is creatine that is keeping the engine running smoothly even after so many hours.

    I will like once every week or two have a poor night sleep. These days I take twice the dose and I don't feel like I'm sleep deprived at all. Feels like cheating! And apparently no side effects at all so far. Well, maybe I'm working too much.

    1. iamacyborg · · focus · HN ↗
      I take creatine daily, have done for well over a year. I also run 5-6 days a week and lift twice a week.

      I’ve previously stopped taking it for a couple months and noticed no real difference in physical or mental ability.

      1. ffsm8 · · focus · HN ↗
        You may not have taken enough. You need 15-20g/day for mental benefits. And long term, at least 2+ weeks.
        1. treetalker · · focus · HN ↗
          If you would, please explain or point me to the material where you get your higher dosage recommendation. (I always heard and understood proper dosage to be 5–7.5g/day, 10g/day at the most. I’d like to correct my error if I’m mistaken.)
          1. DenisM · · focus · HN ↗
            Huberman podcast has some coverage
            1. goobatrooba · · focus · HN ↗
              Sorry i dont have strong views on the fact under question but 1) pointing to an entire podcast is not a very helpful suggestion 2) I listened to a few episodes on issues I know about and can just say that the guy is speaking with confidence but just making it all up. So much false info or at best hearsay repackaged as supposedly scientific advice.
              1. DenisM · · focus · HN ↗
                My options are: provide keywords to research with your favorite agent, do the research for you, or withhold the keyword suggestions.

                Which option seems preferable to you?

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