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Creatine uptake enhances antitumor immunity

185 points · 227 comments · lormayna

  1. rgbrgb · · focus · HN ↗
    worth noting that there’s evidence both ways… tumor cells may like it too:

    - Loo et al. 2015 found color cancer cells can use it as fuel and blocking the creatine cut metastasis in mice [0]

    - zhang et al 20921 found it promoting mouse colon and breast cancer models [1]

    not an expert in any way, but i’m guessing it depends on cancer type and there doesn’t seem to be human data either way. as a cautious person w a lot of familial cancer, i cycled off after i looked into it.

    [0]: <a href="https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;25601461&#x2F;" rel="nofollow">https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;25601461&#x2F;

    [1]: <a href="https:&#x2F;&#x2F;doi.org&#x2F;10.1016&#x2F;j.cmet.2021.03.009" rel="nofollow">https:&#x2F;&#x2F;doi.org&#x2F;10.1016&#x2F;j.cmet.2021.03.009

    1. KetoManx64 · · focus · HN ↗
      The article just won&#x27;t load on my phone, but what did they feed the mice during the study?
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