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Creatine uptake enhances antitumor immunity

185 points · 227 comments · lormayna

  1. nsbk · · focus · HN ↗
    This is such a crazy substance. I'm 43 and I feel like I have more energy than I have ever had before. I started taking it during recovery from a bad ankle fracture since it helps building muscle mass. Once the ankle was better I took up CrossFit, and kept on taking creatine because why not, it helps replenish ATP so I will be able to give the extra-push when working out, I thought.

    What is blowing my mind though is that at $dayjob my team is going through a crazy crunch to deliver a very strategic project and some of us are pushing 10-12h days often. I'm in hour 12 today for the second day in a row, and my head is not tired at all. Turns out the brain also uses a lot of ATP too, specially during demanding cognitive tasks so I guess it is creatine that is keeping the engine running smoothly even after so many hours.

    I will like once every week or two have a poor night sleep. These days I take twice the dose and I don't feel like I'm sleep deprived at all. Feels like cheating! And apparently no side effects at all so far. Well, maybe I'm working too much.

    1. torben-friis · · focus · HN ↗
      Mind that, while the "creatine high dose to fight drowsiness" hack works and has no side effects (other than upset stomachs), the lost sleep still does it thing. You don't notice day to day but it will catch up to you eventually in many bad ways.
      1. nsbk · · focus · HN ↗
        Definitely! I would not recommend it to make up for lack of sleep for extended periods of time.

        One of the things I'm trying to do better lately is to have a good sleep hygiene. Sun in the eyes early in the morning, no caffeine for the first 60 waking minutes of the day (adenosine absorption period), no screens 2 hours before bed and whatnot. Still, some nights I will just wake up in the middle of the night and won't be able to get back to sleep, then it's when I feel creatine helps

        Edit: Typo

        1. wafflemaker · · focus · HN ↗
          How much do you eat and how\when?

          Also @ others in this thread.

          I'm eating 10g, in the morning, don't have tendency for stomach issues, taking it mostly to have more energy at a physical job.

          I can definitely run longer on it before being tired, but not sure what to observe for other effects?

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