‹ BackHN Continuity

Thread

Creatine uptake enhances antitumor immunity

185 points · 227 comments · lormayna

  1. robotsquidward · · focus · HN ↗
    - Enhances ANTI-tumor... sounds good - ANTI-tumor immunity... sounds bad? - Read first few paragraphs as a typical medical rube, got nowhere

    So, creatine = good?

    1. gbil · · focus · HN ↗
      I mean the summary ends with pretty clear message

      > …and support the use of creatine supplementation as a strategy to augment DC-based cancer immunotherapy.

      So it seems that from this research the outcome is indeed creatine = good

    2. el_benhameen · · focus · HN ↗
      Don’t worry, if you aren’t confused enough there’s also this to send you through another cycle! <a href="https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;33811821&#x2F;" rel="nofollow">https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;33811821&#x2F;
      1. goda90 · · focus · HN ↗
        That link sent me into a neverending redirect and reCAPTCHA loop, so very confused.
        1. ffsm8 · · focus · HN ↗
          He did say it&#x27;s a cycle after all! Scnr

          Title:

          &gt; Creatine promotes cancer metastasis through activation of Smad2&#x2F;3

          Tldr is basically that creatine helps body cells (in rats) to grow. Regardless wherever they&#x27;re bad (cancer) or good (muscle). At least that&#x27;s how I understood that study the last time I came across it. So probably stop using creatine when you&#x27;ve a cancer that&#x27;s growing. Or its liable to use the creatine to turbocharge it&#x27;s growth

    3. readthenotes1 · · focus · HN ↗
      Original title may be clearer?

      Creatine uptake promotes dendritic cell activation and enhances antitumor immunity

      1. lormayna · · focus · HN ↗
        Original title is too long, I had to shorten it
    4. HedonicEscal8r · · focus · HN ↗
      &quot;Immunity&quot; = &quot;immune system activity.&quot; &quot;Anti-tumor immunity&quot; = &quot;immune system activity against tumors.&quot;
      1. pinkmuffinere · · focus · HN ↗
        Thankyou!! I&#x27;m sure if you have experience in the medical space this sort of thing seems obvious, but to me (non-medical), the original phrasing was so confusing. Your explanation makes sense.
    5. adammarples · · focus · HN ↗
      Anti-missile shielding
    6. dessimus · · focus · HN ↗
      &quot;But you get your choice of toppings.&quot; &quot;That&#x27;s good!&quot; &quot;The toppings contain potassium benzoate... ...that&#x27;s bad.&quot;
      1. pak9rabid · · focus · HN ↗
        Can I go now?
Open on Hacker News to reply ↗

Unofficial Hacker News client; not affiliated with Y Combinator.