Most of the body doesn't regenerate because there was not enough evolutionary pressure. Even with regeneration you could still easily die from some severe injury, blood loss or disease. While salamander regeneration is impressive, it has its limitations. For example, no known adult salamander can regenerate an entirely removed eye. Also if you chop a salamander, it will not regenerate like a Planarian worm, it will just die. And a fun fact, Axolotls can regrow a limb yet cannot regenerate an adult eye lens.
Also, although the article is mostly true, there are some inaccuracies:
>> Neurons and cardiac muscle cells don't reproduce after childhood
There is some evidence showing a slow cell turnover in cardiac muscle, estimated around ~1% per year in young adults, falling toward ~0.5% in older people. Most neurons don't regenerate, but there an evidence that some parts of the adult brain (such as hippocampus) still produce new neurons, although the number is very low.
Liver regeneration is not perfect either: <a href="https://www.youtube.com/watch?v=rOv7Sr3X-eo" rel="nofollow">https://www.youtube.com/watch?v=rOv7Sr3X-eo .
Exactly, limbs are quite large portion of the body, that's why many think salamanders would have no problems with regenerating all other smaller body parts. And that's not the case.
senfiaj · · focus · HN ↗
Also, although the article is mostly true, there are some inaccuracies:
>> Neurons and cardiac muscle cells don't reproduce after childhood
There is some evidence showing a slow cell turnover in cardiac muscle, estimated around ~1% per year in young adults, falling toward ~0.5% in older people. Most neurons don't regenerate, but there an evidence that some parts of the adult brain (such as hippocampus) still produce new neurons, although the number is very low.
Liver regeneration is not perfect either: <a href="https://www.youtube.com/watch?v=rOv7Sr3X-eo" rel="nofollow">https://www.youtube.com/watch?v=rOv7Sr3X-eo .
BrtByte · · focus · HN ↗
senfiaj · · focus · HN ↗
mcv · · focus · HN ↗