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Why is the liver so weirdly regenerative?

576 points · 293 comments · jbotz

  1. Noe2097 · · focus · HN ↗
    > And even after taking [immunosuppressants], there’s a 30% chance the kidney will be rejected within 10 years. This is not helpful.

    To the author: thank you, you made my day. It had been a very, very long time since I last read an article on the Internet that felt written by a human being - with humor, some poetry, and science.

    1. varispeed · · focus · HN ↗
      Why nature did this? So that 3rd parties don't engage in organ swaps?

      Almost like Apple with component serialisation.

      1. srdjanr · · focus · HN ↗
        In this case nature was just indifferent to transplants as they weren't a thing even 100 years ago.

        As others have explained, foreign cells usually meant trouble, so fighting them by default was a good choice. And there was no pressure to allow transplants specifically, because they didn't exist.

        Also, (I think) you usually need a transplant later in life, after reproduction, so too late for evolution to affect it. So even if we had transplants for millions of years, it might not have made much difference either.

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