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Why is the liver so weirdly regenerative?

576 points · 293 comments · jbotz

  1. cityofdelusion · · focus · HN ↗
    The author suggests humans are overturned to repairing skin and blood, but I strongly disagree. People with problems with wound healing can face significant disability and mortality. Wound healing allows us to have surgery and close up with simple sutures. A lot of complications post-surgery in humans and other animals are specifically from impaired wound healing capability. It’s a good trade-off: nearly everyone will eventually get cut open by accident or on purpose. The skins ability to heal is so amazing that many types of wounds require nothing other than some cleaning, the body will fully clot, bridge, build, and scar back to most retained function. Wound healing allows us to heal large burns and even simply leave many wounds open to air.

    Complications with healing are pretty brutal. Necrosis, amputation, infection are all common without the built-in cascade we have.

    1. seethishat · · focus · HN ↗
      Many problems with would healing are due to nutrient deficiencies. For example, people who are sulfur deficient will heal and recover much slower than those who are not.

      That's why so many professional athletes take MSM (Methylsulfonylmethane). Their bodies would not be able to recover as quickly without the extra sulfur.

      1. shiandow · · focus · HN ↗
        Huh, another reason to eat more spinach I suppose.
        1. hobo123 · · focus · HN ↗
          If you like all those carotenoids and oxalates... If rather just have some onions for sulphur instead.
          1. podocarp · · focus · HN ↗
            Blanche spinach, try not to eat them raw. Speaking of oxalates, I did not know yam leaves were inedible. Saw a little tender shoot, bit a little piece off. Tastes like mushroom. I don't think it's toxic but it's like eating glass.
            1. IAmBroom · · focus · HN ↗
              Blanching does nothing to oxalic acid.

              And that "eating glass" comment is related to how I know. I boiled a wild "edible" (skunkweed leaves) in 3 changes of water; what I should have done is either dry it completely or (better) treat it with lye. Bad memory mistake. Yeah: eating glass shards.

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