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Why is the liver so weirdly regenerative?

576 points · 293 comments · jbotz

  1. Noe2097 · · focus · HN ↗
    > And even after taking [immunosuppressants], there’s a 30% chance the kidney will be rejected within 10 years. This is not helpful.

    To the author: thank you, you made my day. It had been a very, very long time since I last read an article on the Internet that felt written by a human being - with humor, some poetry, and science.

    1. varispeed · · focus · HN ↗
      Why nature did this? So that 3rd parties don't engage in organ swaps?

      Almost like Apple with component serialisation.

      1. pocksuppet · · focus · HN ↗
        The way your body detects foreign cells is the same way your body detects foreign cells. It detects anything that doesn't have your, specific, randomly-generated at conception, friend-or-foe markers.
        1. Ancapistani · · focus · HN ↗
          Would those markers be usable as a natural UUID?
          1. Terr_ · · focus · HN ↗
            Not the major HLA markers, no, because there's a ~25% chance it'll match for two siblings [0] and can sometimes match other relatives.

            Once you start looking at even more factors, you start reinventing a regular DNA-matching test.

            [0] The "Birthday Paradox" makes the odds of confusion even higher with more siblings.

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