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Claude Opus 5.5

1806 points · 1134 comments · km144

  1. ApolloFortyNine · · focus · HN ↗
    >Because Opus 5.5 is comparable to Claude Mythos 5.1 in biology and cybersecurity, we’re deploying it with safeguards similar to those on Claude Fable 5.1. Vetted organizations can apply today to our Life Sciences Verification Program to use Opus 5.5 for biology research. In the coming weeks we will also be expanding access to our Cyber Verification Program, and verified cybersecurity practitioners will be able to use Opus 5.5 for their work.

    Ah, they're spreading their limits to all their models it seems. Definitely not a good thing long term in my opinion.

    1. sys32768 · · focus · HN ↗
      Fable and now Opus 5.5 won't answer my college student's prompt about Alzheimer's and immune response.

      ChatGPT 6 Pro answered it without issue.

      1. debesyla · · focus · HN ↗
        I am honestly still confused about this limitation. I can understand cybersecurity, because mass "hacking" can be automated and Claude itself can help you do it, but biology...? Is it that easy to manufacture and distribute viruses and whatnot?
        1. toss1 · · focus · HN ↗
          Considering there are many high-school competitions in genetic editing, some listed at [0] as well as a whole biohacker culture, and labs providing gene sequencing as a service e.g., [1,2], we can reasonably assume it is not beyond the reach of some garage lab to accidentally or deliberately spread a deadly pathogen if it can find the right sequence.

          So, yes, having an unconstrained frontier AI doing the searching and analysis to find the right (i.e., wrong and deadly) sequence would massively increase the odds some garage biohacker or small aggrieved nation-state starting the next pandemic.

          [0] <a href="https:&#x2F;&#x2F;www.sciencebuddies.org&#x2F;projects-lessons-activities&#x2F;genetic-engineering&#x2F;high-school" rel="nofollow">https:&#x2F;&#x2F;www.sciencebuddies.org&#x2F;projects-lessons-activities&#x2F;g...

          [1] <a href="https:&#x2F;&#x2F;www.genewiz.com&#x2F;public&#x2F;services&#x2F;sanger-sequencing" rel="nofollow">https:&#x2F;&#x2F;www.genewiz.com&#x2F;public&#x2F;services&#x2F;sanger-sequencing

          [2] <a href="https:&#x2F;&#x2F;plasmidsaurus.com&#x2F;" rel="nofollow">https:&#x2F;&#x2F;plasmidsaurus.com&#x2F;

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