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Two parallel neural ectoderm progenitors contribute to the developing brain

664 points · 258 comments · emigre

  1. bethekind · · focus · HN ↗
    > They identified two different brain progenitor cells. One, which expresses a gene called Otx2, is destined to become the forebrain and midbrain. The other, which expresses a gene called Gbx2, is committed to forming the hindbrain. They showed that these two cell populations never overlap; they are mutually exclusive from the earliest stages of development.

    Very cool. Never thought the brain could have two completely different ancestors

    1. kazinator · · focus · HN ↗
      Fun fact: the hindbrain progenitor cell is shaped like a little lizard.
      1. akk0 · · focus · HN ↗
        The lizard brain, not because it resembles the brain of a lizard, but because it's made up of a trillion tiny lizards
        1. TeMPOraL · · focus · HN ↗
          I bet you can tune hyperparameters on the MRI so that the resulting image makes the lizard brain look like a lizard, too.
        2. machomaster · · focus · HN ↗
          Because they are proudly causing animalistic, degenerate behavior like Lizzo.
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