Thread

ER visits for gambling disorders doubled after expanded online gambling market

164 points · 157 comments · geox

nullc · 1789583148 · focus · HN ↗
I have never felt anything about gambling. Most boring thing ever. I don't feel anything about investment, and wrote automation to track mine because it's all so boring.
I wouldn't tempt fate to try to expose myself more, but it doesn't seem like I contain whatever is required to form these addictions.
Has it been studied if some people are just much more vulnerable than others, and are there predictive factors?
1. bunderbunder · 1789583711 · focus · HN ↗
  Yes. One interesting example is that compulsive gambling is a side effect of a certain class of drugs for treating Parkinson’s disease.
  <a href="https://parkinsonsjournal.com/en/parkinsons-disease/gambling-disorder" rel="nofollow">https://parkinsonsjournal.com/en/parkinsons-disease/gambling...
  1. fragmede · 1789589041 · focus · HN ↗
    Another interesting thing is that GLP-1s anecdotally treat compulsive gambling.
  2. mrguyorama · 1789593002 · focus · HN ↗
    That's because parkisons drugs can upregulate a certain protein that is implicated in all forms of addiction that feature that kind of "seeking" behavior and modification of the reward system!
    <a href="https://en.wikipedia.org/wiki/FOSB#Role_in_addiction" rel="nofollow">https://en.wikipedia.org/wiki/FOSB#Role_in_addiction
    We found that if you give an addicted rat a chemical which suppresses the expression of this gene, it will improve their addiction situation, reduce seeking behaviors, etc.
    We found that in 2015.

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