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Autism is genetic – and why this information matters now

100 points · 116 comments · AndrewDucker

  1. profsummergig · · focus · HN ↗
    So many misconceptions in this writeup.

    Here's one: even if it were genetic, there could be triggering environmental factors that trigger the onset of autism (I'm just giving a hypothetical example, not making a claim here).

    1. nomel · · focus · HN ↗
      For example, 45% reduction in symptoms from fecal transplant: <a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=48158494">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=48158494

      &gt; Prior to the study, 83% of participants had &quot;severe&quot; autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cut-off for mild ASD.

      Incredible! Sure, there could be a genetic component to what flourishes, or ever seeded, in one&#x27;s microflora, but there&#x27;s definitely some external complexities involved here.

      1. donkey_brains · · focus · HN ↗
        Of all the misguided, abusive studies. It beggars belief that a board somehow approved this.

        What happened here is simple: the autistic kids got better at masking in order to placate the researchers who were shoving poop up their butts. In the hope of making it stop.

        1. sokka_h2otribe · · focus · HN ↗
          to be honest I doubt people were masking in response to poop shoving, poop shoving is not the worst and presumably the control group just had non-poop

          what seems more plausible to me would be ~&lt;&lt;poop helped something, something made life easier, autistic life is less obvious and disruptive to non-autistics when life is easier&gt;&gt;

          1. dns_snek · · focus · HN ↗
            There was no control group.

            &gt; We note that due to the open-label nature of this initial trial, all of the assessments are subject to placebo effect, however the long-term improvements we observed here are promising.

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