‹ BackHN Continuity

Thread

Autism is genetic – and why this information matters now

100 points · 116 comments · AndrewDucker

  1. mlboss · · focus · HN ↗
    > Autism is genetic. You’re born autistic and you’re autistic for life. Most autistic people are autistic because of genes they got from their parents. This is why autism often runs in families. Much less commonly, other factors can play a role, but usually in combination with genes from parents. There isn’t a single ‘autism gene’. Thousands of genes combine to make a person autistic. Scientists have identified many of these genes, but they think there are still many more to find. And there is no genetic test for autism. We don't fully understand how genes combine to make a person autistic. It is complex and no simple test can give an accurate answer. Genetic testing cannot predict whether a child will be autistic or not, and it can’t be used to diagnose someone as autistic.

    Autism is genetic but we cannot do genetic testing and prove that you have autism. Seems like a very circular reasoning.

    1. mcv · · focus · HN ↗
      I would expect it's not caused by genes themselves, but by control DNA. That's where a lot of the subtle structural stuff happens. But that's also hard to test for. It's like how you can't test how tall someone is going to be.

      I've also read ages ago in Scientific American that the difference between our brains and chimp brains is almost entirely in control DNA, not in genes. It matters a lot, but is often overlooked. (It used to be called "junk DNA", before people realised how important it was.)

Open on Hacker News to reply ↗

Unofficial Hacker News client; not affiliated with Y Combinator.